Stat Down becomes Stat Up. Ultra Secret RoomTreasure RoomTreasure Room shop item pool, x, paper, Makes all of Isaac's familiars stronger and bigger, Causes most familiars to deal double damage, Has no effect on most familiars that scale with Isaac's tear damage, * key master pool, key beggar pool, key judgement pool, shop room pool, shop item pool, red, heart, This means the trinket does nothing if your active item isn't fully charged, Single-use active items are consumed as normal, Doors can be opened without using up a key, However, when entering the door you are taken to a blue womb room with enemies to defeat. This means some effects such as R U A WIZARD pills only fire tears in one direction, When used, you charge forwards for a second. UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Bethany, Spawns a random pedestal item from the current room's item pool, In exchange, turns one heart container or 2 soul hearts into a broken heart. Only contact poison has this effect - poison from tears doesn't work, UNLOCK: Unlock this item by beating Satan with Lilith, *, green, lips, kiss, drip, drop, serpents kiss, serpent kiss, Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player, This allows for a full 360 degree tear firing radius, Can be overridden by other tear modifiers such as Mom's Knife or Brimstone, Every time you leave the room this effect turns off until you press a shoot button again, Tears are replaced with the ability to charge and fire a laser ring that travels across the room, The size of the ring will depend on how long you charge it, The laser ring does damage scaling based on charge, from 25% at minimum to 100% at max, Rings have infinite range and travel until they hit a wall, Multiple Tech X stacks - every one taken adds another laser ring (doesn't affect your fire rate), * tech 10, tech ten, donut laser rings, vr, headset, visor, Allows you to create one brown tunnel and one blue tunnel in the floor, that can be used to teleport between wherever you placed each one, This item will let you port out of the devil room but not back into it, Very useful in the boss rush and challenge rooms, *, scalpel, red, silver, white, grey, gray, metal, knife, cut, Isaac's tears now travel directly forwards following a beam of light, but will also move sideways based on your player movement, Allows for more accurate correction when firing tears, as their direction can be controlled even after they have been fired, If you switch the direction in which you are firing tears, the beam of light and all your tears will also be transported to the new direction, Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size for 5 seconds and also run away from Isaac, Shrunk enemies can be crushed and killed by walking over them, After firing tears for 3 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring which deals a lot of damage to any enemies inside it, The ring deals damage equal to your tear damage rapidly to any enemies in contact with it, for a total of 30 ticks of damage, You have to keep the fire button held down for the full 3 seconds to cause this effect, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Azazel, In addition to tears, Isaac now holds a spear infront of him which deals damage equal to 2 times your tear damage. It's one of the best Isaac Repentance items for its long-term health-saving potential. While held there is a small chance when using a tarot card or pill that a copy of it will be dropped on the floor next to you, +0.2 Damage Up for each 'evil' item you have, Items classed as evil in this case are Black Candle, Ceremonial Robes, Abaddon, Goat Head, Match Book, Missing Page 2, Safety Pin, UNLOCK: Unlock this item by beating Greed Mode with Eve, Invincibility lasts longer after getting hit (Increased i-frames), This makes it possible to use the Blood Donation machine twice from one hit of damage, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Samson, *, bandana, sling, white, knot, blindfold, +15% chance to get a double item room to spawn on the next floor, If the effect activates, two items spawn in your item room, however only one can be taken (Same effect as the More Options item), The chance doubles to +30% with the effect from Mom's Box, Automatically opens all shop room doors for free, UNLOCK: Unlock this trinket by donating 666 coins to the Greed Donation Machine, UNLOCK: Keeper starts with this trinket after beating Satan with Keeper, Forces the Greed and Super Greed mini bosses to no longer appear in shops or secret rooms, Holding Rib of Greed increase your chance to receive coin drops, UNLOCK: Unlock this trinket by beating Ultra Greed with Keeper, Donating to a Donation Machine has a chance to heal Isaac for a full red heart or spawn a Beggar, UNLOCK: Unlock this item by beating The Lamb boss with Keeper, Destroying poops now gives you a blue fly, While held, you heal for half a red heart every time you use a key to open a door or golden chest, Changes all half red hearts into full hearts, Hearts dropped from Tainted Magdalene's mechanic will be always full red hearts, *, red, brown, grey, gray, necklace, moms locket, mom locket, While this trinket is held you have a significantly lower chance to find spacebar/active items, It will cause passive items to spawn except when the game cannot generate any more passive items and will then instead choose spacebar/active items, Some hard coded spacebar items from bosses and mini-bosses (i.e. Characters ?, Paralysis, Retro Vision, I'm Excited, While held, gives you an orbital that blocks enemy shots and deals contact damage equal to 3.5 per tick, While the active key is held down, Isaac gains +0.5 Speed and all of your orbitals spin faster and deal more damage, Orbital damage is equal to 1.5 x OrbitalDamage + 6 while this effect is active, On death enemies now fire tears in random directions, which can damage other enemies, The amount of tears created by this effect depends on the total health of the enemy killed. Interestingly enough, the beam will look like a G clef symbol. on enemy death, on room clear, on damage taken etc. Any other enemies hit by these shards will become frozen too, Frozen enemies are considered dead by the game, and won't unfreeze or move again. : No effect. Once you've beaten Mother once, a door will appear at the starting room in Depths II, which leads to the Mausoleum/Gehenna floors. The effect is shown visually in 3 stages with the character's belly getting larger each time until it finally gives birth to a familiar. It's the run that keeps on giving and continues to get stronger the farther you get. According to the Bible, "Brimstone", which is possibly the ancient name for sulfur, evokes the acrid odor of volcanic activity. REPENTANCE - +0.2 Speed Up (Used to be -0.1 Speed before Repentance). Trinkets However, If you also have flying you will always take damage, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, bomb, A random chance when you take damage to get an invincibility shield for 7 seconds, The chance to get an invincibility shield is affected by your luck stat and at +10 Luck it will activate every time you get hit, Converts all negative pills into their positive counterparts e.g. Not to be confused with Blood Clot, an item. Each use of this item gives +0.7 Damage Up, -0.18 Speed Down and the ability to destroy most obstacles for the current room. Not to be confused with Blood Clot, an item. Clots returning back to Eve deal 3x damage as they suck back in, The type of heart consumed to create a clot will give it different abilities: Soul Hearts = More health, Black Hearts = Dark Matter effect, Eternal Hearts = Sacred Heart effect, Gold Hearts = Midas Touch effect, Bone Hearts = Compound Fracture effect, Rotten Hearts = Less health, Tainted Eve starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: This item comes along with Tainted Eve. For example rerolling Plan C (ID = 475) changes it into the Broken Glass Cannon, which is a hidden item with ID = 474, Items that are yet to be unlocked will also be skipped over, preventing you from getting items you don't have access to yet, UNLOCK: Unlock this item by defeating Delirium as Tainted Isaac, Upon taking damage you have a chance to drop the heart that you just lost. This does not work with items that grant a charged attack but also override Technology's costume, e.g. Based on the Steam Workshop mod created by Niro, A familiar with a charged attack, that spawns a line of creep on the floor which damages enemies that walk over it, The familiar and its creep will change randomly when Isaac uses a pill, Possible creep types include green (deals damage), black (slows enemies), red (deals damage, forms a line with a larger puddle), yellow (deals damage, forms a short-range cone) and white (slows enemies, forms a ring), Added as part of the Afterbirth+ Booster Pack #5. Bosses Photo: Alexandra Wyman/WireImage. Following the path takes you to an abandoned mineshaft, which leads you to a pedestal with the Knife Piece. To help with range, the orbit is now also offset based on the current direction Isaac is shooting, * item room, treasure room, item room pool, grey, gray, asteroid, silver, ball, Creates a friendly blue spider when you kill an enemy, Spiders are spawned at the location where the enemy died, * item room, treasure room, item room pool, pink, smile, E. Coli turns normal enemies into poop if they touch you, Enemies can turn into poop even if they do not do contact damage, allowing you to apply the effect without taking damage, Can be combined with Midas Touch to turn enemies into Golden Poop, This does not work on mini-bosses and bosses. UNLOCK: Unlock this item by defeating Mother in the Corpse II as ??? Chapters Symptoms of a blood clot include: throbbing or cramping pain, swelling, redness and warmth in a leg or arm. This will increase Brimstone's hit times from 2 to a maximum of 4 times, effectively doubling the damage. Characters This can be anything that would normally drop from a chest including pedestal items, When used, this item causes Isaac to become humongous for 30 seconds, While huge, Isaac is invincible and can crush objects, doors and enemies, For the duration of the effect this gives you a x4 Damage Multiplier and +2.0 Range Up, but your rate of fire goes way down. Most items that change tear color will also give Brimstone an exotic appearance, but they do not combine and only one color effect is shown. "This could be a sign of a superficial or small blood . It appears as an alchemical symbol for sulfur. No longer drops black hearts like it used to. Isaac appears demonic with large curved horns and an angry expression. Brimstone's item icon originally comes from the alchemical symbol for. Cathedral: 1 Angel Room Item + 1 Eternal Heart, Pandora's Box considers XL floors to always be the first floor of a chapter, Alternative floors drop the same stuff e.g. Objects ipecac isaac seedhegelian theory of social change. ( : Guppy's Tail Mom's Purse Bob's Curse Pageant Boy Scapular Infestation The Mulligan Habit Spirit Of The Night Ankh Celtic Cross Mitre Fate The Black Bean Holy Grail Dead Dove Pyro 3 Dollar Bill Mom's Coin Purse Box), ( : Guppy's Paw IV Bag Best Friend Remote Detonator Guppy's Head Prayer Card Notched Axe Crystal Ball Crack The Sky The Candle D20 Spider Butt Dad's Key Portable Slot White Pony Blood Rights), Books: The Bible The Book of Belial The Necronomicon Book Of Revelations Book of Shadows Anarchist Cookbook The Book Of Sin Monster Manuel The run that keeps on giving and continues to get stronger the farther you get a sign a. One of the best Isaac Repentance items for its long-term health-saving potential gives damage. 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